Dr Nicole Cardoso

Senior Investigator I AMR Biology

Dr Nicole Cardoso is a molecular and micro- biologist with over a decade of experience in mycobacterial research.

She obtained her PhD from the University of the Witwatersrand in South Africa and her postgraduate and postdoctoral research focused on the characterization of vulnerable genes and pathways in Mycobacterium tuberculosis that could potentially serve as novel drug targets. The areas of research included respiration, nitrogen metabolism and molybdenum cofactor biosynthesis.

Dr Cardoso joined H3D in 2020 and was a part of the TB Biology team until early 2023. During that time, she was responsible for routine primary and secondary screening assays, designing and performing experiments for mechanism of action deconvolution of hit compounds and was involved in academic projects focused on basic biology. The projects she has worked on have been in various stages of pre-clinical drug discovery from formal hit assessment to late lead optimization.

Since late 2023, Dr Cardoso has been leading the AMR Biology team and has expanded the platform to include molecular biology expertise and tools for Gram-negative bacteria, with a particular focus on the priority pathogen Acinetobacter baumannii.